<?xml version="1.0" encoding="UTF-8"?>

<channelml xmlns="http://morphml.org/channelml/schema" 
    xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" 
    xmlns:meta="http://morphml.org/metadata/schema" 
    xsi:schemaLocation="http://morphml.org/channelml/schema  http://www.neuroml.org/NeuroMLValidator/NeuroMLFiles/Schemata/v1.8.1/Level2/ChannelML_v1.8.1.xsd"
    units="Physiological Units">

    <meta:notes>A channel from Maex, R and De Schutter, E. Synchronization of Golgi and Granule Cell Firing in a 
    Detailed Network Model of the Cerebellar Granule Cell Layer</meta:notes>
    
    <channel_type name="Gran_KA_98">
        
        <status value="stable">
            <meta:comment>Verified equivalence of NEURON and GENESIS mapping to orig GENESIS impl from www.tnb.ua.ac.be</meta:comment>
            <meta:comment>Updated to post v1.7.3 new ChannelML format</meta:comment>
            <meta:contributor>
                <meta:name>Padraig Gleeson</meta:name>
            </meta:contributor>
        </status>
        
        <meta:notes>A-type K channel, with rate equations expressed in tau and inf form</meta:notes>
    
        <meta:authorList>
            <meta:modelAuthor>
                <meta:name>Maex, R.</meta:name>
            </meta:modelAuthor>
            <meta:modelAuthor>
                <meta:name>De Schutter, E.</meta:name>
            </meta:modelAuthor>
            <meta:modelTranslator>
                <meta:name>Padraig Gleeson</meta:name>
                <meta:institution>UCL</meta:institution>    
                <meta:email>p.gleeson - at - ucl.ac.uk</meta:email>
            </meta:modelTranslator>
        </meta:authorList>
        
        <meta:publication>
           <meta:fullTitle>Maex, R and De Schutter, E. 
           Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the 
           cerebellar Granule Cell Layer. J Neurophysiol, Nov 1998; 80: 2521 - 2537</meta:fullTitle>
           <meta:pubmedRef>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=9819260&amp;dopt=Abstract</meta:pubmedRef>
        </meta:publication>     
   
        <meta:neuronDBref>
            <meta:modelName>K channels</meta:modelName>
            <meta:uri>http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3</meta:uri>
        </meta:neuronDBref>

        
        <current_voltage_relation cond_law="ohmic" ion="k" default_gmax="1.14567" default_erev="-90">
            
            <q10_settings q10_factor="1" experimental_temp="17.350264793"/>
            <offset value="10"/>
            
            <gate name="m" instances="3">
                <closed_state id="m0"/>
                <open_state id="m"/>
                     
                <time_course  name="tau" from="m0" to="m" expr_form="generic"
                              expr="0.410 * ((exp (( ((v) + 43.5) / (-42.8))))) + 0.167" />
                <steady_state name="inf" from="m0" to="m" expr_form="sigmoid"
                              rate="1" scale="-19.8" midpoint="-46.7" />
                    
            </gate>
        
            <gate name="h" instances="1">
                <closed_state id="h0"/>
                <open_state id="h"/>
                     
                <time_course  name="tau" from="h0" to="h" expr_form="generic"
                              expr="10.8 + (0.03 * v) + (1 / (57.9 * (exp (v *0.127)) + (134e-6 * (exp (v * -0.059)))))" />
                <steady_state name="inf" from="h0" to="h" expr_form="sigmoid"
                              rate="1" scale="8.4" midpoint="-78.8" />
                    
            </gate>
        </current_voltage_relation> 
        
        
    </channel_type>
</channelml>


